- Asymmetric Catalytic Synthesis of Thiochromenes via an Acyl Transfer-Initiated Cascade.
Asymmetric Catalytic Synthesis of Thiochromenes via an Acyl Transfer-Initiated Cascade.
Organic letters (2016-07-08)
Nicholas A Ahlemeyer, Vladimir B Birman
PMID27384085
摘要
A novel, reagent-free catalytic transformation of α,β-unsaturated thioesters into 2-substituted thiochromenes has been developed, with carbon dioxide as the only byproduct. Amidine-based catalysts, particularly homobenzotetramisole and its analogues, achieve high enantioselectivities and yields in this process.
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