- The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells.
The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells.
Scientific reports (2017-04-08)
Mei-Chuan Chen, Yi-Chiu Kuo, Chia-Ming Hsu, Yi-Lin Chen, Chien-Chang Shen, Che-Ming Teng, Shiow-Lin Pan
PMID28387244
摘要
Patients with ovarian cancer are typically diagnosed at an advanced stage, resulting in poor prognosis since there are currently no effective early-detection screening tests for women at average-risk for ovarian cancer. Here, we investigated the effects of MT-6, a derivative of moscatilin, in ovarian cancer cells. Our investigation showed that MT-6 inhibited the proliferation and viability of ovarian cancer cells with submicromolar IC
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