- A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphisms.
A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphisms.
Chemical communications (Cambridge, England) (2013-08-08)
Wei Shen, Cai Le Lim, Zhiqiang Gao
PMID23923128
摘要
A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction.
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