1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.

1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.

Bioorganic & medicinal chemistry letters (2005-06-14)

Raman K Bakshi, Qingmei Hong, J T Olson, Zhixiong Ye, Iyassue K Sebhat, David H Weinberg, Tanya MacNeil, Rubana N Kalyani, Rui Tang, William J Martin, Alison Strack, Erin McGowan, Constantin Tamvakopoulos, Randy R Miller, Ralph A Stearns, Wei Tang, D Euan Maclntyre, Lex H T van der Ploeg, Arthur A Patchett, Ravi P Nargund

PMID15951175

摘要

The discovery of 1-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid analogs as potent human melanocortin-4 selective agonists is described.

材料

货号

品牌

产品描述

421626

Sigma-Aldrich

(S)-1,2,3,4-四氢-3-异喹啉羧酸, 97%

214930

Sigma-Aldrich

1,2,3,4-四氢-3-异喹啉羧酸盐酸盐, 96%