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  • Diosmin--isolation techniques, determination in plant material and pharmaceutical formulations, and clinical use.

Diosmin--isolation techniques, determination in plant material and pharmaceutical formulations, and clinical use.

Natural product communications (2013-06-07)
Anna Bogucka-Kocka, Michał Woźniak, Marcin Feldo, Janusz Kockic, Katarzyna Szewczyk
摘要

Diosmin is a naturally occurring flavone glycoside used in the treatment of venous diseases. In this review, we present the clinical aspects of the use of diosmin preparations in venous stasis, hemorrheologic disorders and vein wall remodeling. Because of its multiple applications in biology and its many therapeutic activities, research on isolation and identification of diosmin is of high relevance. The aim of this review is to present an overview of techniques of isolation and separation of diosmin in plant material, pharmaceutical formulations such as Daflon, Diosed and Dioven tablets, and biological fluids.

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地奥司明, European Pharmacopoeia (EP) Reference Standard
Supelco
地奥司明, analytical standard
地奥司明, European Pharmacopoeia (EP) Reference Standard