- Effect of NlpE overproduction on multidrug resistance in Escherichia coli.
Effect of NlpE overproduction on multidrug resistance in Escherichia coli.
Antimicrobial agents and chemotherapy (2010-03-10)
Kunihiko Nishino, Seiji Yamasaki, Mitsuko Hayashi-Nishino, Akihito Yamaguchi
PMID20211889
摘要
NlpE, an outer membrane lipoprotein, functions during envelope stress responses in Gram-negative bacteria. In this study, we report that overproduction of NlpE increases multidrug and copper resistance through activation of the genes encoding the AcrD and MdtABC multidrug efflux pumps in Escherichia coli.