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Merck

SML0647

Sigma-Aldrich

芬那西泮标准液

≥97% (HPLC)

别名:

7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-Bromo-5-(2-chlorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one, BD 98, Fenazepam

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About This Item

经验公式(希尔记法):
C15H10BrClN2O
CAS号:
分子量:
349.61
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥97% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 20 mg/mL, clear

儲存溫度

−20°C

InChI

1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChI 密鑰

CGMJQQJSWIRRRL-UHFFFAOYSA-N

生化/生理作用

Phenazepam is the benzodiazepine that exhibit anticonvulsive, anxiolytic, sedative and hypnotic effects in humans and experimental animals. Phenazepam is an agonist of the γ-Aminobutyric acid A (GABAA)-benzodiazepine receptor chloride channel complex.

特點和優勢

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形圖

Exclamation markHealth hazard

訊號詞

Danger

危險分類

Eye Irrit. 2 - Lact. - Muta. 1B - Repr. 1B

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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[Evaluation of the effect of phenazepam and seduxen on the functional state of the cardiovascular system in the acute phase of an infarct].
G Lukhanana
Vrachebnoe delo, (10)(10), 15-18 (1983-10-01)
N Ia Golovenko et al.
Farmakologiia i toksikologiia, 43(2), 144-148 (1980-03-01)
The distribution pattern of 14C-phenazepam and some of its metabolites in the liver, brain and blood plasma at a prolonged (45 days) administration to rats does not differ from that after a single administration. The liver and brain demonstrated an
Peter D Maskell et al.
Journal of forensic and legal medicine, 19(3), 122-125 (2012-03-07)
In the past few years there has been concern in Western Europe and in the US about the rise in abuse of phenazepam, a benzodiazepine that was originally developed in the USSR in the mid- to late 1970s.(1-4) Although phenazepam
Jon B Stephenson et al.
Journal of analytical toxicology, 37(1), 25-29 (2012-10-18)
Phenazepam use in the state of Georgia has increasingly become a trend for a drug market looking at new and different recreational drugs. This paper examines the psychomotor effects of phenazepam on individuals and their ability to operate a motor
John Martin Corkery et al.
Human psychopharmacology, 27(3), 254-261 (2012-03-13)
Phenazepam (fenazepam; 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; PNZ, 'Bonsai') is a benzodiazepine developed in the former Soviet Union during the 1970s to treat neurological disorders, epilepsy, and alcohol withdrawal syndrome. Its recreational use appears to have increased over recent years. Because of the lack

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