推荐产品
生物源
goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
mouse, human, canine, pig, rat, bovine
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NPR3(4883)
一般說明
Natriuretic peptide receptor 3 (NPR3) is a natriuretic peptide receptor. It is expressed in endothelial cells, vessels, endocrine glands, lungs and kidneys. The gene encoding NPR3 is localized on human chromosome 5p14-p13. The protein consists of a 450-amino acid extracellular ligand-binding domain, a transmembrane region and a cytoplasmic tail.
免疫原
Peptide with sequence C-HRELREDSIRSHFS, from the C-terminal region of the protein sequence according toNP_000899.1
應用
Anti-NPR3 (C-terminal) antibody produced in goat has been used in Western blotting.
生化／生理作用
Natriuretic peptide receptor 3 (NPR3) has a role in the clearance of natriuretic peptides and modulates their plasma levels. It is associated with essential hypertension. NPR3 may be involved in signaling pathways and is associated with inhibitory G protein.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Deborah Carper et al.
Cell reports, 32(8), 108075-108075 (2020-08-28)
Atrial natriuretic peptide (ANP) is a cardiac hormone controlling blood volume and pressure in mammals. It is still unclear whether ANP controls cold-induced thermogenesis in vivo. Here, we show that acute cold exposure induces cardiac ANP secretion in mice and humans.
Association of NPRA and NPRC gene variants and hypertension in Mongolian population.
Chang PY
Genetics and molecular research : GMR (2015)
Natriuretic peptide receptor-3 gene (NPR3): nonsynonymous polymorphism results in significant reduction in protein expression because of accelerated degradation.
Pereira NL
Circulation. Cardiovascular Genetics (2013)
Attenuated atrial natriuretic peptide-mediated
lipolysis in subcutaneous adipocytes of obese
type 2 diabetic men
lipolysis in subcutaneous adipocytes of obese
type 2 diabetic men
Kenneth Verboven
Clinical Science (2016)
NPR-C gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a multicenter study.
Hu Q
Oncotarget (2016)
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