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Merck

S8251

Sigma-Aldrich

氯化琥珀胆碱二水合物 二水合物

98.0-102.0%, solid

别名:

琥珀酰氯化胆碱

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About This Item

线性分子式:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
CAS号:
分子量:
397.34
Beilstein:
3922827
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

化驗

98.0-102.0%

形狀

solid

顏色

white

溶解度

H2O: complete 100 mg/ml, clear to slightly hazy, colorless
H2O: soluble (unstable at pH > 9.)

起源

Novartis

SMILES 字串

O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C

InChI

1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

InChI 密鑰

FFSBEIRFVXGRPR-UHFFFAOYSA-L

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應用

氯化琥珀胆碱用于研究非洲爪蟾 半胱氨酸环受体的门控机制。4,5

生化/生理作用

琥珀胆碱是胆碱能拮抗剂和神经肌肉阻断剂。它诱导肌肉膜上乙酰胆碱受体的去极化和肌肉中钾的流出,导致乙酰胆碱受体表达上调的个体发生低钾血症。3
胆碱能拮抗剂,可诱导乙酰胆碱神经元膜的长期去极化;神经肌肉阻断剂。

特點和優勢

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处

重構

溶液可以在 4℃ 下储存数天。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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