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About This Item
经验公式（希尔记法）:
C11H10BrN3
CAS号:
分子量:
264.12
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
品質等級
化驗
>99% (HPLC)
形狀
solid
溶解度
DMSO: >20 mg/mL
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
Brc1ccc2ncnc(NCC=C)c2c1
InChI
1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15)
InChI 密鑰
BCPOLXUSCUFDGE-UHFFFAOYSA-N
應用
SMER28 may be used in mTOR-mediated signaling studies.
生化／生理作用
SMER28 is a small molecule modulator of mammalian autophagy; enhances A53T alpha-synuclein clearance in PC-12 cells independent of rapamycin treatment; appears to act independent of the mTOR pathway, but combined treatment with saturating rapamycin concentration enhances the effect of either compound alone on A53T alpha-synuclein clearance; autophagy inducers may prove useful in the treatment of neurodegenerative and infectious diseases and cancer.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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