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Merck

P4553

Sigma-Aldrich

6-磷酸葡糖酸脱氢酶 来源于酵母

lyophilized powder, ≥3.0 units/mg solid

别名:

6-磷酸- D -葡萄糖酸盐:NADP + 2-氧化还原酶(脱羧酶), 6-磷酸葡糖酸脱氢酶 来源于酵母

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

yeast

品質等級

形狀

lyophilized powder

比活性

≥3.0 units/mg solid

分子量

52 kDa

儲存溫度

2-8°C

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一般說明

来自酵母的6-磷酸葡萄糖酸脱氢酶包含NADP +结合结构域、α螺旋疏水相互作用结构域和C-末端结构域。它以二聚体的形式存在,C末端区域对于底物的结合和释放至关重要。

應用

来自酵母的6-磷酸葡萄糖酸脱氢酶已被用于确定细胞裂解物中的己糖激酶(HK)和木糖还原酶(XR)活性。

生化/生理作用

通过测量NAD +或NADP +的减少来确定酶活性。据信高水平的NADPH会抑制该酶,而6-磷酸葡萄糖酸酯则可激活该酶

單位定義

在存在NADP+的条件下,在37°C下,每分钟1个单位将1.0μmol的6-磷酸-D葡萄糖酸氧化为D-核糖5-磷酸和CO2

抑制劑

产品编号
说明
价格

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Enhancement of xylose uptake in 2-deoxyglucose tolerant mutant of Saccharomyces cerevisiae
Kahar P, et al.
Journal of Bioscience and Bioengineering, 111(5), 557-563 (2011)
Ai-Hua Jin et al.
BMC structural biology, 7, 28-28 (2007-04-21)
Alpha-conotoxins have exciting therapeutic potential based on their high selectivity and affinity for nicotinic acetylcholine receptors. The spacing between the cysteine residues in alpha-conotoxins is variable, leading to the classification of sub-families. BuIA is the only alpha-conotoxin containing a 4/4
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
He W, et al.
BMC Structural Biology, 7(1), 38-38 (2007)
G Martínez-Drets et al.
Journal of bacteriology, 130(3), 1139-1143 (1977-06-01)
6-Phospho-D-gluconate:NAD+ 2-oxidoreductase (decarboxylating) (NAD+-6PGD) was detected in several slow-growing strains of rhizobia, and no activity involving NADP+ was found in the same extracts. By contrast, fast-growing strains of rhizobia had NADP+-6PGD activity; most of them also had NAD+-6PGD activity. NAD+-6PGD
M Zelewski et al.
Biochemistry international, 19(5), 1057-1065 (1989-11-01)
The effect of starvation-refeeding transitions on the activity of malic enzyme and hexosemonophosphate shunt dehydrogenases in lipogenic and non-lipogenic tissues from rats was investigated. Starvation of the rats caused a decrease of malic enzyme activity in the liver, white and

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