推荐产品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
NB2, monoclonal
分子量
antigen 500 kDa
包含
15 mM sodium azide
物種活性
vertebrates, chicken
技術
indirect immunofluorescence: 1:400 using frozen sections of animal skeletal muscle
western blot: suitable
同型
IgG1
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
chicken ... NEB(101748402)
一般說明
Nebulin is a 700kDa protein which is expressed in skeletal muscles. It possesses 35 amino acid repeats and a C terminal serine-rich and SH3 domains.
Nebulin is also localized to cardiac muscle. Monoclonal Anti-Nebulin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
特異性
Localizes nebulin in skeletal muscle of a wide variety of species from cold-blooded vertebrates to man. Does not crossreact with smooth or cardiac muscle, non-muscle tissue and cultured cells. Localizes nebulin within the I band of skeletal muscle sections by indirect immunofluorescence.
免疫原
chicken breast nebulin.
應用
Monoclonal Anti-Nebulin antibody produced in mouse has been used in:
- immunohistochemistry
- fluorescent immunostaining
- western blotting
生化／生理作用
Nebulin associates with the Z-line and thin actin filament in a sarcomere. It may function as a regulator of sarcomere thin filament length. The protein also acts as a structural link between sarcomeres. Nebulin interacts with the capping protein CapZ and has a role in controlling the localization of actin filaments.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A 7.5-kb 3'-Terminal cDNA Sequence of Chicken Skeletal Muscle Nebulin Reveals Its Actin Binding Regions.
Suzuki T
Zoological Science (2000)
Identification of chicken nebulin isoforms of the 31-residue motifs and non-muscle nebulin.
Joo YM
Biochemical and Biophysical Research Communications (2004)
James D Morton et al.
Meat science, 143, 129-136 (2018-05-12)
High pressure processing (HPP) of pre-rigor longissimus thoracis (strip loin) from prime and bull animals substantially decreased the shear force and improved consumer eating attributes of the final meat product. The improved tenderness in both prime and bull meat was
Clinical phenotype, muscle MRI and muscle pathology of LGMD1F
Peterle E, et al.
Journal of Neurology, 260(8), 2033-2041 (2013)
Clinical phenotype, muscle MRI and muscle pathology
of LGMD1F
of LGMD1F
Enrico Peterle
Journal of Neurology (2013)
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