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Merck

G0299

Sigma-Aldrich

原薯蓣皂苷

from Dioscorea spp., ≥98% (HPLC)

别名:

Furostanol I

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About This Item

经验公式(希尔记法):
C51H84O22
CAS号:
分子量:
1049.20
分類程式碼代碼:
12352212
NACRES:
NA.25

生物源

Dioscorea spp.

化驗

≥98% (HPLC)

形狀

powder

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

InChI

1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1

InChI 密鑰

LVTJOONKWUXEFR-UEZXSUPNSA-N

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一般說明

原薯蓣皂苷是一种存在于多种植物物种中的甾体皂苷。它由苷元和糖苷基团组成,并常作为草本壮阳药的活性成分使用 蒺藜被用于中国传统医学和印度医学中。

應用

原薯蓣皂苷已被用于在体外传统条件下,研究胡芦巴和藜麦提取物对 α-淀粉酶和胰脂肪酶活性的影响 。它也被作为标准品用于对三神经灵芝提取物甾体皂苷的结构表征研究中。

生化/生理作用

原薯蓣皂苷对消化酶具有显著的抑制作用,例如 α-淀粉酶和胰脂肪酶。它被认为可以增加睾酮、促黄体激素、脱氢表雄酮、二氢睾酮和硫酸脱氢表雄酮的水平,同时改善人类和动物的性欲和精子生成。它表现出抗肿瘤活性,尤其是对白血病、结肠癌和前列腺癌。
芦笋中发现的皂苷植物化学成分。心脏保护和抗高血脂剂。针对人癌症细胞系的细胞毒性作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ke Hu et al.
Planta medica, 68(4), 297-301 (2002-05-04)
Protodioscin (NSC-698 796) is a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of urinary bladder and renal tumor for centuries. To systematically evaluate its
K Gauthaman et al.
Life sciences, 71(12), 1385-1396 (2002-07-20)
Tribulus terrestris (TT) has long been used in the traditional Chinese and Indian systems of medicine for the treatment of various ailments and is popularly claimed to improve sexual functions in man. Sexual behaviour and intracavernous pressure (ICP) were studied
Teresa Herrera et al.
Food chemistry, 270, 509-517 (2018-09-04)
Ethanol extracts (EE) from fenugreek and quinoa seeds with different total content of inhibitory compounds (TIC, total saponin plus phenolic) were prepared with and without concentration of TIC (CEE -concentrated EE-, and EE, respectively). Their inhibitory activity on pancreatic lipase
Yonghong Liang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 974, 75-82 (2014-12-03)
Steroid saponins are a class of naturally existing substances widely distributed in the plants of Smilacaceae. Their biological activities have been attracting the interest of scientists in the chemical field for the past few years. To our best knowledge, there

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