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Merck
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Key Documents

AV00022

Sigma-Aldrich

Anti-CFLAR antibody produced in rabbit

IgG fraction of antiserum

别名:

Anti-CASP8 and FADD-like apoptosis Regulator

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

55 kDa

物種活性

human, bovine

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CFLAR(8837)

一般說明

CFLAR is a regulator of apoptosis that is thought to be cleaved by caspase-8. Rabbit Anti-CFLAR antibody recognizes canine, human, mouse, rat, bovine, and pig CFLAR.

免疫原

Synthetic peptide directed towards the N terminal region of human CFLAR

應用

Rabbit Anti-CFLAR antibody can be used for western blot assays at 1.25μg/ml.

序列

Synthetic peptide located within the following region: HQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLA

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Sireesha V Garimella et al.
Breast cancer research : BCR, 16(2), R41-R41 (2014-04-22)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to its receptors, TRAIL-receptor 1 (TRAIL-R1) and TRAIL-receptor 2 (TRAIL-R2), leading to apoptosis by activation of caspase-8 and the downstream executioner caspases, caspase-3 and caspase-7 (caspase-3/7). Triple-negative breast cancer (TNBC) cell lines with

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