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Merck
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Key Documents

257M-1

Sigma-Aldrich

GCDFP-15 (23A3) Mouse Monoclonal Antibody

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.41

生物源

mouse

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

23A3, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (257M-14)
vial of 0.5 mL concentrate (257M-15)
bottle of 1.0 mL predilute (257M-17)
vial of 1.0 mL concentrate (257M-16)
bottle of 7.0 mL predilute (257M-18)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

同型

IgG2a

控制

breast, breast carcinoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... PIP(5304)

一般說明

GCDFP-15 is a 15 kD glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. Approximately 70% of breast carcinomas are labeled with antibody to GCDFP-15. Colorectal carcinomas, lung carcinoma, mesothelimas rarely stain with this antibody. Because of its specificity for breast carcinoma (up to 99%), this antibody is often used in a screening panel in the appropriate clinical situation, often for a woman with metastasis of unknown primary.

品質


IVD

IVD

IVD

RUO

聯結

GCDFP-15 Positive Control Slides, Product No. 257S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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A H Ormsby et al.
Journal of the American Academy of Dermatology, 32(5 Pt 1), 711-716 (1995-05-01)
For accurate classification of cutaneous metastatic carcinoma, reliable tumor-specific immunohistochemical markers would be valuable. Our purpose was to analyze the sensitivity, specificity, and positive predictive value of gross cystic disease fluid protein-15 (GCDFP-15) and estrogen receptor protein (ERP) for diagnosing
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 227-228 (2014)
P Viacava et al.
Virchows Archiv : an international journal of pathology, 432(3), 255-260 (1998-04-09)
GCDFP-15, a glycoprotein identified in the cyst fluid of cystic breast disease, is considered to be a marker of apocrine differentiation. Studies on GCDFP-15 localization in adult normal tissues are lacking, and no information on GCDFP-15 expression during fetal development
M R Wick et al.
Human pathology, 20(3), 281-287 (1989-03-01)
The identification of metastatic carcinoma of the breast may be difficult in the absence of a previous history of breast cancer. Various immunophenotypic markers have been introduced to aid in this process. A monoclonal antibody directed at a 15-kilodalton (kd)

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