PHR2363

维生素K2-（MK-7）

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: （all-E)–2-（3,7,11,15,19,23,27-七甲基-2,6,10,14,18,22,26-十八碳庚烯基）-3-甲基-1,4-萘二酮
• 经验公式（希尔记法）: C₄₆H₆₄O₂
• CAS号: 2124-57-4
• 分子量: 649.00
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1381119
• API 家族: menaquinone
• 形狀: solid
• CofA: current certificate can be downloaded
• 包裝: pkg of 3x75 mg
• 應用: pharmaceutical small molecule
• 儲存溫度: -10 to -25°C
• InChI: 1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+
• InChI 密鑰: RAKQPZMEYJZGPI-LJWNYQGCSA-N

说明

一般說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Menaquinone -7 is a naphthoquinone derivative and one of the most active sub-type of vitamin K2, with 7 referring to the number of isoprene units in its structure. It is naturally found in fermented dairy products and is considered a nutrient, thereby being found as a component of various nutritional supplements.

應用

This pharmaceutical secondary standard can also be used as follows:

• Ultra high-performance liquid chromatography (UHPLC) based determination of menaquinone-7 and vitamin D₃ in their combined tablet formulation
• Development of a thin-layer chromatographic-densitometric technique for the quantitative analysis of vitamins K and D3 in pharmaceutical tablet formulations and dietary supplements
• Simultaneous determination of vitamin D₃ and K₂ (Menaquinone-4 and Menaquinone-7) in dietary supplements by ultra-high-pressure liquid chromatography (UHPLC)
• Impurity profiling of menaquinone-7 in its active pharmaceutical ingredient (API) samples using HPLC coupled to UV detector
• Analysis of menaquinone-4 and menaquinone-7 by HPLC in combination with tandem mass spectrometry (MS/MS) in human milk samples

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC4030 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable