ALD00602

(–)-PSI Reagent

95%

• 别名: (2S,3aS,6R,7aS)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, (–)-Ψ, Phosphorus-Sulfur Incorporation Reagent
• 经验公式（希尔记法）: C₁₆H₁₆F₅OPS₃
• CAS号: 2245335-70-8
• 分子量: 446.46
• 分類程式碼代碼: 12352101
• NACRES: NA.22

属性

• 化驗: 95%
• 形狀: powder or crystals
• mp: 103-107 °C

说明

應用

Air- and moisture-tolerant, this (-)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (+)-PSI Reagent, is also available (cat# ALD00604).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).

Learn more about PI and PSI reagents

其他說明

Unlocking P(V): Reagents for chiral phosphorothioate synthesis

PSI on OpenFlask

法律資訊

PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable