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Merck

81242

Sigma-Aldrich

聚(乙二醇)

tested according to Ph. Eur., 4,000

别名:

Macrogol 4,000, PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL號碼:
分類程式碼代碼:
12352104
PubChem物質ID:
NACRES:
NA.21

agency

tested according to Ph. Eur.

品質等級

形狀

solid

分子量

3500-4500

應用

pharmaceutical (small molecule)

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般說明

聚(乙二醇)(PEG)是一种无毒的水溶性聚合物。PEG 术语用于分子量低于 20000 的聚合物链,而聚(环氧乙烷)(PEO)是指较高分子量的聚合物。PEG 具有多种生物医学应用。它与 α-环糊精形成复合物。已有研究报道了通过介孔二氧化硅(MS)模板法工程化 PEG 水凝胶颗粒。

應用

聚(乙二醇)可用于以下研究:
  • 用于修饰蛋白质形成循环寿命增加、免疫原性和抗原性降低的缀合物。
  • 用于蛋白质扩散控制运输的水凝胶的制备。
  • 聚(乙二醇)二甲基丙烯酸酯(PEGDM)的制备。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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The clinical efficacy of poly (ethylene glycol)-modified proteins.
Fuertges F and Abuchowski A.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 11(1), 139-148 (1990)
N A Peppas et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 81-87 (1999-10-16)
The use of hydrogels as carriers for protein delivery has been a subject of significant recent research. In our recent work, we have shown that diffusion controlled delivery of proteins from hydrogels containing poly(ethylene glycol) (PEG) can be possible and
Stephanie J Bryant et al.
Annals of biomedical engineering, 32(3), 407-417 (2004-04-21)
In approaches to tissue engineer articular cartilage, an important consideration for in situ forming cell carriers is the impact of mechanical loading on the cell composite structure and function. Photopolymerized hydrogel scaffolds based on poly(ethylene glycol) (PEG) may be synthesized
Complex formation between poly (ethylene glycol) and α-cyclodextrin.
Harada A and Kamachi M.
Macromolecules, 23(10), 2821-2823 (1990)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene

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