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Merck

43301

Supelco

Enalaprilat

analytical standard

别名:

(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline

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About This Item

经验公式(希尔记法):
C18H24N2O5
分子量:
348.39
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥98.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

雜質

5-12 wt. % water

格式

neat

SMILES 字串

O=C(N1CCC[C@H]1C(O)=O)[C@H](C)N[C@H](C(O)=O)CCC2=CC=CC=C2

InChI

1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1

InChI 密鑰

LZFZMUMEGBBDTC-QEJZJMRPSA-N

基因資訊

human ... ACE(1636)

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相关类别

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Brian C Ferslew et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1567-1574 (2014-06-25)
Hepatic uptake and efflux transporters govern the systemic and hepatic exposure of many drugs and metabolites. Enalapril is a pharmacologically inactive prodrug of enalaprilat. Following oral administration, enalapril is converted to enalaprilat in hepatocytes and undergoes translocation into the systemic
Sylwia Magiera et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 79-87 (2015-01-16)
Given the increasing popularity of aliskiren, particularly in combination with angiotensin converting enzyme inhibitor (e.g. enalapril), it is important to determine whether its use in combination with these agents is associated with potentially life threatening safety events. Analytical methods for

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