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Merck
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Key Documents

AB10418

Sigma-Aldrich

Anti-Puma BH3 domain Antibody

from rabbit

别名:

BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Bbc3(170770)

一般說明

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis

特異性

Other species have not been tested.
The antibody reacts with the 21 kDa Puma BH3 domain protein.

免疫原

This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.

應用

Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.

品質

Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.

標靶描述

21 kDa

外觀

Format: Purified

分析報告

Control
Western Blot : Mouse brain lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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