344935

Furin Substrate, Fluorogenic

A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 10⁴ s⁻¹M⁻¹).

• 别名: Furin Substrate, Fluorogenic
• 经验公式（希尔记法）: C₃₇H₅₇N₁₃O₉
• 分子量: 827.93
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic); protect from light
• 顏色: white
• 溶解度: water: 10 mg/mL; DMSO: soluble
• 螢光: λ_ex 360 - 380 nm; λ_em 430-460 nm
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A fluorogenic substrate for furin (k_cat/K_m ~2 X 10⁴ M^-1 s^-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (k_cat/K_m ~6 X 10³ M^-1 s^-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm).

A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (k_cat/K_m ~ 2 x 10⁴ s^-1M^-1).

生化／生理作用

Cell permeable: no

Primary Target
Fluorogenic substrate for furin

Product does not compete with ATP.

Reversible: no

kcat/Km ~ 2 x 104 s-1M-1 for furin

警告

Toxicity: Standard Handling (A)

序列

Pyr-Arg-Thr-Lys-Arg-AMC

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable