GEN-7003

Cationic Liposomes for DNA/RNA delivery

DOTAP:Cholesterol (1:1) containing 0.5% NBD-DOPE (Fluorescent)

• 分類程式碼代碼: 12352211

属性

• 品質等級: 100
• 包含: NBD-DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-; 1,3-benzoxadiazol-4-yl)) as fluorescent label
• 成份: Deionized RNAse-free Water
• 濃度: 0.02 mM (NBD-DOPE); 2 mM (Cholesterol); 2 mM (DOTAP)
• 雜質: 1:1 mol/mol DOTAP:Cholesterol
• 粒徑: 100 nm
• pH值: 7
• 吸光率: _{460/535 nm}

说明

一般說明

Cationic liposomes are traditionally used for the delivery of genetic materials such as various types of DNA (pDNA, cDNA, CpG DNA, oligonucleotide, antisense oligonucleotide), various types of RNA such as (siRNA, mRNA) and nucleic acid mimics (NAMs). The positive, cationic charge of the lipids is used to neutralize the negative charge of nucleic acids and results in greater encapsulation efficiency, cellular uptake and endosomal delivery.

應用

Drug delivery
Gene delivery
Lipid-protein interactions

儲存和穩定性

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

法律資訊

Genesome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

免責聲明

For research use only

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable