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Merck

UBB

ubiquitin B

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(22187) ubiquitin B
  • Rat(192255) ubiquitin B
  • cow(281370) ubiquitin B
  • naked mole-rat(101702552) ubiquitin B
  • domestic guinea pig(100722422) ubiquitin B
  • Zebrafish(550134) ubiquitin B
  • chicken(396190) ubiquitin B
  • Horse(100049794) ubiquitin B
  • domestic cat(101091319) ubiquitin B
  • dog(479513) ubiquitin B

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Antibodies

货号
说明
物种反应性
应用
抗-磷酸化-泛素(Ser65), from rabbit, purified by affinity chromatography,
物种反应性
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
应用
immunocytochemistry
western blot
Anti-Ubiquitin Lys63 Antibody, clone HWA4C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
ELISA
affinity binding assay

western blot
Anti-Ubiquitin Antibody, clone 5J3V7, Rabbit Monoclonal, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Monoclonal Anti-UBB antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-UBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot

Proteins

货号
说明
物种
泛素 人, recombinant, expressed in E. coli (N-terminal histidine tagged),
物种
human
泛素 人, ≥95% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal FLAG® tagged), lyophilized powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human UBB,
物种
human
MISSION® esiRNA, targeting mouse Ubb,
物种
mouse