TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Human TNFRSF1B (7133), Mouse Tnfrsf1b (21938), Rat Tnfrsf1b (156767), cow TNFRSF1B (338033), sheep TNFRSF1B (100240715), domestic guinea pig Tnfrsf1b (100723273), naked mole-rat Tnfrsf1b (101712824), Zebrafish tnfrsf1b (100037357), chicken TNFRSF1B (395083), dog TNFRSF1B (487437)
- Human(7133) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
- Mouse(21938) tumor necrosis factor receptor superfamily, member 1b
- Rat(156767) tumor necrosis factor receptor superfamily, member 1b
- cow(338033) tumor necrosis factor receptor superfamily, member 1B
- sheep(100240715) tumor necrosis factor receptor superfamily, member 1B
- domestic guinea pig(100723273) tumor necrosis factor receptor superfamily, member 1B
- naked mole-rat(101712824) tumor necrosis factor receptor superfamily, member 1B
- Zebrafish(100037357) tumor necrosis factor receptor superfamily, member 1B
- chicken(395083) tumor necrosis factor receptor superfamily, member 1B
- dog(487437) tumor necrosis factor receptor superfamily, member 1B
- domestic cat(101080392) tumor necrosis factor receptor superfamily, member 1B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
human
immunocytochemistry
western blot
western blot
Anti-TNF Receptor II, antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-TNFRSF1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot
Anti-TNFRSF1B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
human, mouse
western blot
Proteins
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
human
Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
human
sTNF-receptor Type II human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
human