跳转至内容
Merck

TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

别名:
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
物种:
UniProtKB ID:
基因ID:
  • Human(7133) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
  • Mouse(21938) tumor necrosis factor receptor superfamily, member 1b
  • Rat(156767) tumor necrosis factor receptor superfamily, member 1b
  • cow(338033) tumor necrosis factor receptor superfamily, member 1B
  • sheep(100240715) tumor necrosis factor receptor superfamily, member 1B
  • domestic guinea pig(100723273) tumor necrosis factor receptor superfamily, member 1B
  • naked mole-rat(101712824) tumor necrosis factor receptor superfamily, member 1B
  • Zebrafish(100037357) tumor necrosis factor receptor superfamily, member 1B
  • chicken(395083) tumor necrosis factor receptor superfamily, member 1B
  • dog(487437) tumor necrosis factor receptor superfamily, member 1B
  • domestic cat(101080392) tumor necrosis factor receptor superfamily, member 1B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
Human soluble TNF Receptor 2 ELISA Kit, for serum, plasma for serum, plasma, cell culture supernatant and urine,
物种
human
恒河猴TNFR2 ELISA, for serum, plasma and cell culture supernatants,
物种

Antibodies

货号
说明
物种反应性
应用
Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
物种反应性
human
应用
immunocytochemistry
western blot
Anti-TNF Receptor II, antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
Anti-TNFRSF1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-TNFRSF1B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse
应用
western blot
Anti-TNFR2/TNFRSF1B Antibody, clone 7S1K0, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot

Proteins

货号
说明
物种
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
物种
human
Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
物种
human
sTNF-receptor Type II human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TNFRSF1B,
物种
human
MISSION® esiRNA, targeting mouse Tnfrsf1b,
物种
mouse