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Merck

STAT5A

signal transducer and activator of transcription 5A

别名:
MGF, STAT5
物种:
UniProtKB ID:
基因ID:
  • Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
  • Mouse(20850) signal transducer and activator of transcription 5A
  • Rat(24918) signal transducer and activator of transcription 5A
  • dog(490968) signal transducer and activator of transcription 5A
  • Horse(100052904) signal transducer and activator of transcription 5A
  • domestic cat(101090913) signal transducer and activator of transcription 5A
  • cow(282375) signal transducer and activator of transcription 5A
  • sheep(443419) signal transducer and activator of transcription 5A
  • naked mole-rat(101723770) signal transducer and activator of transcription 5A
  • domestic guinea pig(100716811) signal transducer and activator of transcription 5A

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ELISA

货号
说明
物种
检测培养细胞系中磷酸化STAT5 (pTyr694)的基于细胞的ELISA试剂盒, 96 assays,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Phospho-STAT5A-Y694 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-STAT5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-phospho-STAT5A (pSer780) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-phospho-STAT5A (pTyr694) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-STAT5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Proteins

货号
说明
物种
STAT5,His 标记 人, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human STAT5A,
物种
human
MISSION® esiRNA, targeting mouse Stat5a,
物种
mouse