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Merck

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

别名:
PP-1A, PP1A, PP1alpha, PPP1A
物种:
UniProtKB ID:
基因ID:
  • Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
  • Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
  • dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme
  • naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
  • cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
  • sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme

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Antibodies

货号
说明
物种反应性
应用
Anti-PP1-α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-PPP1CA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Phospho-PPP1CA-T320 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Rabbit anti-PPP1CA Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-PPP1CA, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rabbit, rat
应用
western blot

Proteins

货号
说明
物种
蛋白磷酸酶-1 催化亚单位,α-亚型 来源于兔, 5,000-15,000 units/mg protein, recombinant, expressed in E. coli, lyophilized powder,
物种
domestic rabbit
PP1A, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PPP1CA,
物种
human
MISSION® esiRNA, targeting mouse Ppp1ca,
物种
mouse