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Merck

MTNR1A

melatonin receptor 1A

别名:
MEL-1A-R, MT1
物种:
UniProtKB ID:
基因ID:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A

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Small Molecule - Agonist

货号
说明
物种
6-Hydroxymelatonin, ,
物种
human
拉梅尔通, ,
物种
human
阿戈美拉汀, ≥98% (HPLC),
物种
human

Small Molecule - Antagonist

货号
说明
物种
Luzindole, ≥90%,
物种
human
阿戈美拉汀, ≥98% (HPLC),
物种
human
褪黑素, powder, ≥98% (TLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

Small Molecule - Ligand

货号
说明
物种
褪黑素, powder, ≥98% (TLC),
物种
human

Small Molecule - Precursor

货号
说明
物种
N-乙酰-5-羟色胺, ≥99% (HPLC), powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MTNR1A,
物种
human