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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

别名:
CLG4, CLG4A, MMP-II, MONA, TBE-1
物种:
UniProtKB ID:
基因ID:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

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ELISA

货号
说明
物种
人类 MMP-2 ELISA 试剂盒, for serum, plasma, cell culture supernatant,
物种
human
小鼠 MMP-2 ELISA 试剂盒, for serum, plasma and cell culture supernatant,
物种
mouse
大鼠MMP-2 ELISA, for serum, plasma and cell culture supernatants,
物种
rat

Antibodies

货号
说明
物种反应性
应用
抗-MMP2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti- MMP2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-MMP-2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
抗-MMP2, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
应用
immunohistochemistry
western blot
Anti-MMP2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
马立马司他, ≥98% (HPLC),
物种
human, rat, mouse
CP-101537, ≥98% (HPLC),
物种
human, rat, mouse
CP-471474, ≥98% (HPLC),
物种
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
物种
human, rat, mouse

Proteins

货号
说明
物种
基质金属蛋白酶-2 人, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
物种
human
基质金属蛋白酶-2 人, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
物种
human
基质金属蛋白酶2 来源于小鼠, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
物种
mouse, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Mmp2,
物种
mouse
MISSION® esiRNA, targeting human MMP2,
物种
human