跳转至内容
Merck

KLRC1

killer cell lectin-like receptor subfamily C, member 1

别名:
CD159A, NKG2, NKG2A
物种:
UniProtKB ID:
基因ID:
  • Human(3821) Summary: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(16641) killer cell lectin-like receptor subfamily C, member 1
  • Rat(29683) killer cell lectin-like receptor subfamily C, member 1
  • naked mole-rat(101713681) killer cell lectin-like receptor subfamily C, member 1
  • cow(783419) NKG2A-like
  • cow(514897) killer cell lectin-like receptor subfamily C, member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-KLRC1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-KLRC1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human KLRC1,
物种
human