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Merck

GAD1

glutamate decarboxylase 1 (brain, 67kDa)

别名:
CPSQ1, GAD, SCP
物种:
UniProtKB ID:
基因ID:
  • Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
  • Mouse(14415) glutamate decarboxylase 1
  • Rat(24379) glutamate decarboxylase 1
  • fruit fly(38484) Glutamic acid decarboxylase 1
  • cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
  • dog(478794) glutamate decarboxylase 1 (brain, 67kDa)
  • chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic guinea pig(100271904) glutamate decarboxylase 1
  • naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
  • sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)

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ELISA

货号
说明
物种
人GAD1 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-GAD67 Antibody, clone 1G10.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
抗-GAD1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-GAD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2911, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GAD1,
物种
human
MISSION® esiRNA, targeting mouse Gad1,
物种
mouse