E2F2
E2F transcription factor 2
别名:
E2F-2
物种:
Human E2F2 (1870), Mouse E2f2 (242705), Rat E2f2 (684111), Domestic Rabbit E2F2 (100346379), naked mole-rat E2f2 (101711793), domestic guinea pig E2f2 (100714679), fruit fly E2f2 (35381), cow E2F2 (617024), Horse E2F2 (100057866), domestic cat E2F2 (101098067) ...展开
UniProtKB ID:
基因ID:
- Human(1870) Summary: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008]
- Mouse(242705) E2F transcription factor 2
- Rat(684111) E2F transcription factor 2
- Domestic Rabbit(100346379) E2F transcription factor 2
- naked mole-rat(101711793) E2F transcription factor 2
- domestic guinea pig(100714679) E2F transcription factor 2
- fruit fly(35381) E2F transcription factor 2
- cow(617024) E2F transcription factor 2
- Horse(100057866) E2F transcription factor 2
- domestic cat(101098067) E2F transcription factor 2
- dog(100684439) E2F transcription factor 2
- chicken(425366) E2F transcription factor 2
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Antibodies
货号
说明
物种反应性
应用
Anti-E2F2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot