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Merck

DAAM1

dishevelled associated activator of morphogenesis 1

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(23002) Summary: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]
  • Mouse(208846) dishevelled associated activator of morphogenesis 1
  • Rat(314212) dishevelled associated activator of morphogenesis 1
  • chicken(423532) dishevelled associated activator of morphogenesis 1
  • dog(490714) dishevelled associated activator of morphogenesis 1
  • domestic cat(101098546) dishevelled associated activator of morphogenesis 1
  • Horse(100051203) dishevelled associated activator of morphogenesis 1
  • cow(513742) dishevelled associated activator of morphogenesis 1
  • domestic guinea pig(100719981) dishevelled associated activator of morphogenesis 1
  • naked mole-rat(101726077) dishevelled associated activator of morphogenesis 1
  • sheep(101123636) dishevelled associated activator of morphogenesis 1

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Antibodies

货号
说明
物种反应性
应用
Anti-DAAM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-DAAM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-DAAM1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Monoclonal Anti-DAAM1 antibody produced in mouse, clone 5D3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Monoclonal Anti-DAAM1, (N-terminal) antibody produced in mouse, clone 4H3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
ELISA
proximity ligation assay

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human DAAM1,
物种
human
MISSION® esiRNA, targeting mouse Daam1,
物种
mouse