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Merck

COX10

cytochrome c oxidase assembly homolog 10 (yeast)

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(1352) Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008]
  • Mouse(70383) cytochrome c oxidase assembly protein 10
  • Rat(363617) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • Zebrafish(553384) cytochrome c oxidase assembly homolog 10 (yeast)
  • Thale Cress(819059) protoheme IX farnesyltransferase
  • cow(511440) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • Horse(100073118) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • dog(489515) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • chicken(417329) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • domestic guinea pig(100732273) COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)

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Antibodies

货号
说明
物种反应性
应用
Anti-COX10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-COX10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-COX10 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-COX10 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human COX10,
物种
human
MISSION® esiRNA, targeting mouse Cox10,
物种
mouse