CNTNAP1
contactin associated protein 1
CASPR, CNTNAP, NRXN4, P190
Human CNTNAP1 (8506), Mouse Cntnap1 (53321), Rat Cntnap1 (84008), Zebrafish cntnap1 (386706), chicken CNTNAP1 (428309), dog CNTNAP1 (490960), cow CNTNAP1 (540997), Horse CNTNAP1 (100052467), domestic cat CNTNAP1 (101099341), sheep CNTNAP1 (101111565) ...展开
- Human(8506) Summary: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
- Mouse(53321) contactin associated protein-like 1
- Rat(84008) contactin associated protein 1
- Zebrafish(386706) contactin associated protein 1
- chicken(428309) contactin associated protein 1
- dog(490960) contactin associated protein 1
- cow(540997) contactin associated protein 1
- Horse(100052467) contactin associated protein 1
- domestic cat(101099341) contactin associated protein 1
- sheep(101111565) contactin associated protein 1
- naked mole-rat(101714103) contactin associated protein 1
- domestic guinea pig(100719034) contactin associated protein 1
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immunofluorescence
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immunohistochemistry