CCM2
cerebral cavernous malformation 2
别名:
C7orf22, OSM
物种:
Human CCM2 (83605), Mouse Ccm2 (216527), Rat Ccm2 (305505), Zebrafish ccm2 (436586), chicken CCM2 (420410), cow CCM2 (506450), Horse CCM2 (100065340), domestic cat CCM2 (101100375), dog CCM2 (475502), domestic guinea pig Ccm2 (100716240) ...展开
UniProtKB ID:
基因ID:
- Human(83605) Summary: This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
- Mouse(216527) cerebral cavernous malformation 2
- Rat(305505) cerebral cavernous malformation 2
- Zebrafish(436586) cerebral cavernous malformation 2
- chicken(420410) cerebral cavernous malformation 2
- cow(506450) cerebral cavernous malformation 2
- Horse(100065340) cerebral cavernous malformation 2
- domestic cat(101100375) cerebral cavernous malformation 2
- dog(475502) cerebral cavernous malformation 2
- domestic guinea pig(100716240) cerebral cavernous malformation 2
- naked mole-rat(101711971) cerebral cavernous malformation 2
- sheep(101114100) cerebral cavernous malformation 2
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Antibodies
Product Number
说明
物种反应性
应用
Anti-CCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-CCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CCM2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot
western blot
Anti-CCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
物种反应性
human
应用
immunohistochemistry
Anti-CCM2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot