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Merck

BPGM

2,3-bisphosphoglycerate mutase

别名:
DPGM
物种:
UniProtKB ID:
基因ID:
  • Human(669) Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
  • Mouse(12183) 2,3-bisphosphoglycerate mutase
  • Rat(296973) 2,3-bisphosphoglycerate mutase
  • Zebrafish(436903) 2,3-bisphosphoglycerate mutase
  • dog(482704) 2,3-bisphosphoglycerate mutase
  • domestic cat(101095644) 2,3-bisphosphoglycerate mutase
  • cow(533785) 2,3-bisphosphoglycerate mutase
  • chicken(418172) 2,3-bisphosphoglycerate mutase
  • domestic guinea pig(100722842) 2,3-bisphosphoglycerate mutase
  • naked mole-rat(101706859) 2,3-bisphosphoglycerate mutase
  • sheep(101121089) 2,3-bisphosphoglycerate mutase
  • Domestic Rabbit(100009096) 2,3-bisphosphoglycerate mutase

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Antibodies

货号
说明
物种反应性
应用
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-BPGM (ab2) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human BPGM,
物种
human
MISSION® esiRNA, targeting mouse Bpgm,
物种
mouse