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Merck

BLNK

B-cell linker

别名:
AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca
物种:
UniProtKB ID:
基因ID:
  • Human(29760) Summary: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(17060) B cell linker
  • Rat(499356) B-cell linker
  • Zebrafish(405764) B-cell linker
  • chicken(395733) B-cell linker
  • dog(486814) B-cell linker
  • cow(510393) B-cell linker
  • Horse(100070841) B-cell linker
  • domestic cat(101086423) B-cell linker
  • naked mole-rat(101718500) B-cell linker
  • domestic guinea pig(100712978) B-cell linker
  • sheep(101111241) B-cell linker

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-BLNK antibody produced in mouse, clone 1D7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
proximity ligation assay

western blot
Anti-BLNK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-BLNK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Ms Blnk antibody produced in rabbit, ,
物种反应性
mouse
应用
western blot
Anti-phospho-BLNK (pTyr96) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human BLNK,
物种
human
MISSION® esiRNA, targeting mouse Blnk,
物种
mouse