AXIN1
axin 1
别名:
AXIN, PPP1R49
物种:
Human AXIN1 (8312), Mouse Axin1 (12005), Rat Axin1 (79257), Zebrafish axin1 (57931), cow AXIN1 (504357), Horse AXIN1 (100065116), domestic cat AXIN1 (101088804), dog AXIN1 (490099), chicken AXIN1 (395786), sheep AXIN1 (101122656) ...展开
UniProtKB ID:
基因ID:
- Human(8312) Summary: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
- Mouse(12005) axin 1
- Rat(79257) axin 1
- Zebrafish(57931) axin 1
- cow(504357) axin 1
- Horse(100065116) axin 1
- domestic cat(101088804) axin 1
- dog(490099) axin 1
- chicken(395786) axin 1
- sheep(101122656) axin 1
- domestic guinea pig(100718536) axin 1
- naked mole-rat(101700795) axin 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-AXIN1 antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-Axin1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-Axin-1 Antibody, clone A5, clone A5, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Axin1 (C-terminal region) 兔抗, ~2.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot