AGTR1
angiotensin II receptor, type 1
别名:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
物种:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), Domestic Rabbit AGTR1 (100009164), chicken AGTR1 (396065), domestic cat AGTR1 (101082936), dog AGTR1 (403836), cow AGTR1 (281607)
UniProtKB ID:
基因ID:
- Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- naked mole-rat(101714068) angiotensin II receptor, type 1
- domestic guinea pig(100192325) angiotensin II receptor, type 1
- sheep(443107) angiotensin II receptor, type 1
- Domestic Rabbit(100009164) angiotensin II receptor, type 1
- chicken(396065) angiotensin II receptor, type 1
- domestic cat(101082936) angiotensin II receptor, type 1
- dog(403836) angiotensin II receptor, type 1
- cow(281607) angiotensin II receptor, type 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
抗 AGTR1 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
抗-AT1受体抗体, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
应用
western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, human, mouse, rat
应用
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Small Molecule - Inhibitor
esiRNA
货号
说明
物种