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  • The use of intravenous aminobisphosphonates for the treatment of Paget's disease of bone.

The use of intravenous aminobisphosphonates for the treatment of Paget's disease of bone.

Mini reviews in medicinal chemistry (2009-08-20)
Luigi Gennari, Daniela Merlotti, Giuseppe Mossetti, Domenico Rendina, Vincenzo De Paola, Giuseppe Martini, Ranuccio Nuti
ABSTRACT

Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Neridronate, ≥97% (NMR), solid