999994P

12:0 Diether PC

Avanti Research^™ - A Croda Brand 999994P, powder

• Synonym(s): 1,2-di-0-dodecyl-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₃₂H₆₈NO₆P
• CAS Number: 72593-72-7
• Molecular Weight: 593.86
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (999994P-10mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 999994P
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCC)COCCCCCCCCCCCC)=O

Description

General description

12:0 Diether PC (phosphocholine) is a glycerophospholipid having choline as the alcohol moiety, attached to the phosphate group. It has two dodecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds.

Application

12:0 Diether PC or 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine might be used in small micelles to study the interaction of peptides with model membranes by nuclear magnetic resonance (NMR) experiments.

Biochem/physiol Actions

12:0 Diether PC (phosphocholine) is useful in bicelles formation. Bicelles are suitable to be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. It is found to be a simpler membrane model and is highly compatible with nuclear magnetic resonance (NMR).

Packaging

5 mL Amber Glass Screw Cap Vial (999994P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3