TPM3
tropomyosin 3
Synonyms:
CAPM1, CFTD, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30
Species:
Human TPM3 (7170), Mouse Tpm3 (59069), Rat Tpm3 (117557), Zebrafish tpm3 (373076), domestic cat TPM3 (101099019), dog TPM3 (480137), chicken TPM3 (770103), cow TPM3 (497019), sheep TPM3 (101108973), domestic guinea pig Tpm3 (100728267)
UniProtKB ID:
Gene ID:
- Human(7170) Summary: This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(59069) tropomyosin 3, gamma
- Rat(117557) tropomyosin 3
- Zebrafish(373076) tropomyosin 3
- domestic cat(101099019) tropomyosin 3
- dog(480137) tropomyosin 3
- chicken(770103) tropomyosin 3
- cow(497019) tropomyosin 3
- sheep(101108973) tropomyosin 3
- domestic guinea pig(100728267) tropomyosin 3
- naked mole-rat(101701017) tropomyosin 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TPM3 antibody produced in mouse, clone 2E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TPM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-TPM3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-TPM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry