TPH1
tryptophan hydroxylase 1
Synonyms:
TPRH, TRPH
Species:
Human TPH1 (7166), Mouse Tph1 (21990), Rat Tph1 (24848), chicken TPH1 (395799), domestic cat TPH1 (101098575), Horse TPH1 (100056614), dog TPH1 (611956), cow TPH1 (781941), sheep TPH1 (101113620), domestic guinea pig Tph1 (100718189) ...More
UniProtKB ID:
Gene ID:
- Human(7166) Summary: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
- Mouse(21990) tryptophan hydroxylase 1
- Rat(24848) tryptophan hydroxylase 1
- chicken(395799) tryptophan hydroxylase 1
- domestic cat(101098575) tryptophan hydroxylase 1
- Horse(100056614) tryptophan hydroxylase 1
- dog(611956) tryptophan hydroxylase 1
- cow(781941) tryptophan hydroxylase 1
- sheep(101113620) tryptophan hydroxylase 1
- domestic guinea pig(100718189) tryptophan hydroxylase 1
- naked mole-rat(101710219) tryptophan hydroxylase 1
- Domestic Rabbit(100101558) tryptophan hydroxylase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-Tryptophan Hydroxylase (pSer58) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Tryptophan Hydroxylase antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-TPH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Tryptophan Hydroxylase Antibody, Chemicon®, from sheep,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-Tryptophan Hydroxylase (pSer58) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, sufficient for 10 blots,
Species Reactivity
xenopus, human, mouse, rat
Application
dot blot
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Precursor
Product Number
Description
Species