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Merck

SOX2

SRY (sex determining region Y)-box 2

Synonyms:
ANOP3, MCOPS3
Species:
UniProtKB ID:
Gene ID:
  • Human(6657) Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
  • Mouse(20674) SRY-box containing gene 2
  • Rat(499593) SRY (sex determining region Y)-box 2
  • Zebrafish(378723) SRY-box containing gene 2
  • Horse(100146979) SRY (sex determining region Y)-box 2
  • domestic cat(100379629) SRY (sex determining region Y)-box 2
  • dog(488092) SRY (sex determining region Y)-box 2
  • chicken(396105) SRY (sex determining region Y)-box 2
  • cow(784383) SRY (sex determining region Y)-box 2
  • Goat(100861576) SRY (sex determining region Y)-box 2
  • sheep(101110563) SRY (sex determining region Y)-box 2
  • domestic guinea pig(100714747) SRY (sex determining region Y)-box 2
  • naked mole-rat(101723266) SRY (sex determining region Y)-box 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Sox-2 Antibody, clone 1A2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-sox2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
zebrafish
Application
immunohistochemistry
western blot
Anti-SOX2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, goat, human, mouse, pig, rat
Application
western blot
Anti-SOX2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-SOX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4716, purified immunoglobulin,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Sox2 TAT human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
Sox2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SOX2,
Species
human