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Merck

RLN2

relaxin 2

Synonyms:
H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2
Species:
UniProtKB ID:
Gene ID:
  • Human(6019) Summary: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the protein encoded by this gene consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-RLN2(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RLN2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
Relaxin-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RLN2,
Species
human