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Merck

PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

Synonyms:
Hcam3
Species:
UniProtKB ID:
Gene ID:
  • Human(5137) Summary: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]
  • Mouse(18575) phosphodiesterase 1C
  • Rat(81742) phosphodiesterase 1C
  • fruit fly(34594) CG44007 gene product from transcript CG44007-RG
  • Zebrafish(100536162) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • Horse(100070015) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • domestic cat(101089682) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • dog(475272) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • chicken(420752) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • cow(526211) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • sheep(101121508) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • domestic guinea pig(100726194) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • naked mole-rat(101717015) phosphodiesterase 1C, calmodulin-dependent 70kDa
  • Domestic Rabbit(100347155) phosphodiesterase 1C, calmodulin-dependent 70kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDE1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PDE1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Vinpocetine, ≥98%, solid,
Species
human
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Species
human
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Species
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pde1c,
Species
mouse
MISSION® esiRNA, targeting human PDE1C,
Species
human