NEB
nebulin
Synonyms:
NEB177D, NEM2
Species:
Human NEB (4703), Mouse Neb (17996), Rat Neb (311029), sheep NEB (101118671), domestic guinea pig Neb (100728002), naked mole-rat Neb (101726265), Domestic Rabbit NEB (100328572), fruit fly neb (35293), domestic cat NEB (101086918), cow NEB (407121) ...More
UniProtKB ID:
Gene ID:
- Human(4703) Summary: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy. [provided by RefSeq, Sep 2009]
- Mouse(17996) nebulin
- Rat(311029) nebulin
- sheep(101118671) nebulin
- domestic guinea pig(100728002) nebulin
- naked mole-rat(101726265) nebulin
- Domestic Rabbit(100328572) nebulin
- fruit fly(35293) nebbish
- domestic cat(101086918) nebulin
- cow(407121) nebulin
- Horse(100057773) nebulin
- dog(476149) nebulin
- chicken(374027) nebulin
- Zebrafish(566928) nebulin
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Nebulin antibody produced in mouse, clone NB2, ascites fluid,
Species Reactivity
chicken, vertebrates
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-NEB antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-NEB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species