MAP2K5
mitogen-activated protein kinase kinase 5
Synonyms:
HsT17454, MAPKK5, MEK5, PRKMK5
Species:
Human MAP2K5 (5607), Mouse Map2k5 (23938), Rat Map2k5 (29568), Zebrafish map2k5 (100007679), domestic cat MAP2K5 (101100725), cow MAP2K5 (100295732), Horse MAP2K5 (100052849), dog MAP2K5 (609559), chicken MAP2K5 (415557), sheep MAP2K5 (101104069) ...More
UniProtKB ID:
Gene ID:
- Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
- Mouse(23938) mitogen-activated protein kinase kinase 5
- Rat(29568) mitogen activated protein kinase kinase 5
- Zebrafish(100007679) mitogen-activated protein kinase kinase 5
- domestic cat(101100725) mitogen-activated protein kinase kinase 5
- cow(100295732) mitogen-activated protein kinase kinase 5
- Horse(100052849) mitogen-activated protein kinase kinase 5
- dog(609559) mitogen-activated protein kinase kinase 5
- chicken(415557) mitogen-activated protein kinase kinase 5
- sheep(101104069) mitogen-activated protein kinase kinase 5
- Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
- naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
- domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone M1-E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-MAP2K5, (N-terminal) antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
ANTI-MOUSE MAP2K5 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species