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Merck

KEAP1

kelch-like ECH-associated protein 1

Synonyms:
INrf2, KLHL19
Species:
UniProtKB ID:
Gene ID:
  • Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(50868) kelch-like ECH-associated protein 1
  • Rat(117519) Kelch-like ECH-associated protein 1
  • fruit fly(42062) CG3962 gene product from transcript CG3962-RC
  • cow(532791) kelch-like ECH-associated protein 1
  • dog(476713) kelch-like ECH-associated protein 1
  • domestic cat(101091260) kelch-like ECH-associated protein 1
  • sheep(101113845) kelch-like ECH-associated protein 1
  • domestic guinea pig(100713871) kelch-like ECH-associated protein 1
  • naked mole-rat(101718777) kelch-like ECH-associated protein 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KEAP1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, human, rabbit, rat
Application
immunohistochemistry
western blot
Anti-KEAP1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-KEAP1, clone 7G4B10 Antibody, clone 7G4B10, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry
Anti-KEAP1 Antibody, clone 3B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
ELISA
affinity binding assay

immunocytochemistry

western blot
Anti-KEAP1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Dimethyl Fumarate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Dimethyl fumarate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Dimethyl fumarate, 97%,
Species
human
CDDO Methyl Ester, ≥98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KEAP1,
Species
human