IL24
interleukin 24
Synonyms:
C49A, FISP, IL10B, MDA7, MOB5, ST16
Species:
Human IL24 (11009), Mouse Il24 (93672), Rat Il24 (170819), domestic guinea pig Il24 (100714873), naked mole-rat Il24 (101707178), sheep IL24 (101113424), dog IL24 (609213), cow IL24 (526285), domestic cat IL24 (101095874)
UniProtKB ID:
Gene ID:
- Human(11009) Summary: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(93672) interleukin 24
- Rat(170819) interleukin 24
- domestic guinea pig(100714873) interleukin 24
- naked mole-rat(101707178) interleukin 24
- sheep(101113424) interleukin 24
- dog(609213) interleukin 24
- cow(526285) interleukin 24
- domestic cat(101095874) interleukin 24
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